Progressive Retinal Atrophy, rcd4-PRA

The test detects the mutation (c.3149_3150insC) in the PCARE gene that causes Progressive Retinal Atrophy, rcd4 (rcd4-PRA). The inheritance is autosomal recessive, meaning that only animals carrying two copies of the mutated gene will be affected. Affected dogs experience progressive vision loss with advancing age, leading to complete blindness.
Test application:
- Assessment of the PCARE genotype status in breeding planning
- Differential diagnostics for dogs with eye diseases